Aids Essays (4346 words) - HIVAIDS, HIV, Kaposis Sarcoma

Aids Acquired immunodeficiency syndrome (AIDS). Today, despite the continuing production of better antibiotics since the discovery of penicillin, we are facing an infectious disease against which all these drugs are virtually powerless. This disease is spreading inexorably, killing more people and more people each year. AIDS does not know no national boundaries and does not discriminate by race or sex. It is rampaging not only throughout the United States, but also through Africa, India, China, Russia, Europe, South America, and the Caribbean countries. Even infants and children are at risk. AIDS is similar to the bubonic plague or the BLACK DEATH that killed perhaps one-third in Europe in the 14th century. Yet, the difference from the Black Death and AIDS is that it is in slow motion because the infectious agent that causes AIDS can remain dormant in a person's body for several years before it causes illness, and because death from AIDS can be slow and drawn out once symptoms appear. AIDS is essentially a disease of the immune system. The body's defenses are destroyed and the patient becomes prey to the infections and cancers that would normally be fought off without any trouble. In 1984 it was proved that AIDS is caused by the human immunodeficiency virus (HIV). A virus is a minute infectious particle that enters and kills the immune cells, or lymphocytes. Because it destroys the very mechanism humans rely on for protection, prior to 1996 contracting Aids was considered a death sentence. For many years, 85 to 90 percent of all AIDS patients died within three years. They might have recovered from one infection only to succumb to another a few months later. Between infections they remain weak, emaciated and unable to work or carry on normal activities. In late 1996, almost 15 years after the first reported AIDS cases, researchers made the discovery that a certain combination of newly developed drugs could substantially prolong life in some AIDS patients. But AIDS is a fiendish virus. When researchers cleared it out of a patient's bloodstream, it hid in the lymph nodes. Scientists, figured out how to banish it from the lymph nodes, they found the virus lurking in the brain. Although, there is hope for a cure because they have done some experiments isolating a gene and it has had good results in some people infected with AIDS. The area that many people are concerned is with Southeast Asia-particularly India. At 900 million, India's population is almost double that sub-Saharan Africa, which, with 13.3 million HIV-positive adults, accounts for 60 percent of the world's total adult infections. The major reasons for such spread in India and following Africa is the high rate of their population, poverty rate, and other risk factors all point to a likely explosion. The number of HIV infections worldwide doubled between 1991 and 1996-and that number is expected to double again by the year 2000. By the turn of the century, about 44 million people will have fallen victim to the virus that causes AIDS. The signs of hope do not stop by the reason of Prevention Programs which they have succeeded in reducing HIV-infection rates dramatically among young men in Thailand and young women in Uganda-two of the countries hit hardest by the3 disease. The rate of new infections have also dropped sharply among gay men in the United States, Australia, Canada, and western Europe. However, many ingredients of the AIDS epidemic are still mystery. The cause of AIDS remained uncertain for several years after its discovery. Even now, there are questions about how efficiently the AIDS virus spreads, whether it will kill everyone who gets it, and why the virus is do devastating to the immune system. It's initial spread was in the United States was among groups that are frowned upon by society-homosexuals and intravenous(drug users)- AIDS has a stigma associated with it. This makes the disease difficult to confront rationally. However, people are terrified even by the word of AIDS. The virus does not get transmitted by any body contact neither through the air. However, the disease does not pass from one person to another through the air, by sneezing, on eating utensils, by shaking hands, or through body contact in

Geography and Information About the State of Louisiana

Geography and Information About the State of Louisiana Capital: Baton RougePopulation: 4,523,628 (2005 estimate prior to Hurricane Katrina)Largest Cities: New Orleans, Baton Rouge, Shreveport, Lafayette and Lake CharlesArea: 43,562 square miles (112,826 sq km)Highest Point: Mount Driskill at 535 feet (163 m)Lowest Point: New Orleans at -5 feet (-1.5 m)Louisiana is a state located in the southeastern portion of the United States between Texas and Mississippi and south of Arkansas. It features a distinct multicultural population that was influenced by French, Spanish and African peoples during the 18th century due to colonization and slavery. Louisiana was the 18th state to join the U.S. on April 30, 1812. Prior to its statehood, Louisiana was a former Spanish and French colony.Today, Louisiana is most known for its multicultural events such as Mardi Gras in New Orleans, its Cajun culture, as well as its economy based on fishing in the Gulf of Mexico. As such, Louisiana was severely impacted (like all Gulf of Mexico states) by a large oil spill off of its coast in April 2010. In addition, Louisiana is prone to natural disasters like hurricanes and flooding and has recently been hit by several large hurricanes in recent years. The largest of these was Hurricane Katrina which was a category three hurricane when it made landfall on August 29, 2005. 80% of New Orleans was flooded during Katrina and more than two million people were displaced in the region.The following is a list of important things to know about Louisiana, provided in an effort to educate readers about this fascinating U.S. state. Louisiana was first explored by Cabeza de Vaca in 1528 during a Spanish expedition. The French then began exploring the region in the 1600s and in 1682, Robert Cavelier de la Salle arrived at the mouth of the Mississippi River and claimed the area for France. He named the area Louisiana after the French king, King Louis XIV.Throughout the rest of the 1600s and into the 1700s, Louisiana was colonized by both the French and Spanish but it was dominated by the Spanish during this time. During Spains control of Louisiana, agriculture grew and New Orleans became a major trading port. In addition, during the early 1700s, Africans were brought to the region as slaves.In 1803, the U.S. took control of Louisiana after the Louisiana Purchase. In 1804 the land purchased by the U.S. was divided into a southern part called the Territory of Orleans which eventually became the state of Louisiana in 1812 when it was admitted into the union. After becoming a state, Louisiana continued being influence d by French and Spanish culture. This is shown today in the states multicultural nature and the various languages are spoken there. Today, unlike other states in the U.S., Louisiana is divided into parishes. These are local government divisions that are equivalent to counties in other states. Jefferson Parish is the largest parish-based on population while Cameron Parish is the largest by land area. Louisiana currently has 64 parishes.Louisianas topography consists of relatively flat lowlands located on the coastal plain of the Gulf of Mexico and the Mississippi Rivers alluvial plain. The highest point in Louisiana is along its border with Arkansas but it still below 1,000 feet (305 m). The main waterway in Louisiana is the Mississippi and the states coast is full of slow-moving bayous. Large lagoons and oxbow lakes, like Lake Ponchartrain, are also common in the state.Louisianas climate is considered humid subtropical and its coast is rainy. As a result, it contains many biodiverse marshes. Louisianas inland areas are drier and are dominated by low prairies and low rolling hills. Average temperatures vary based on location within the state and the northern regions are colder in the winters and hotter in the summers than those areas closer to the Gulf of Mexico. Louisianas economy is heavily dependent on its fertile soils and waters. Because much of the states land sits on rich alluvial deposits, it is the U.S.s largest producer of sweet potatoes, rice, and sugarcane. Soybeans, cotton, dairy products, strawberries, hay, pecans, and vegetables are also abundant in the state. In addition, Louisiana is well-known for its fishing industry that is dominated by shrimp, menhaden (mostly used to make fishmeal for poultry) and oysters.Tourism is also a large part of Louisianas economy. New Orleans is especially popular due to its history and the French Quarter. That location has many famous restaurants, architecture and is the home of the Mardi Gras festival which has been held there since 1838.The population of Louisiana is dominated by Creole and Cajun peoples of French ancestry. Cajuns in Louisiana are descended from French colonists from Acadia in what were the present-day Canadian provinces of New Brunswick, Nova Scotia, and Prince Edward Island . Cajuns are mainly settled in southern Louisiana and as a result, French is a common language in the region. Creole is the name given to people born to French settlers in Louisiana when it was still a colony of France. Louisiana is home to some of the most famous universities in the U.S. Some of these include Tulane and Loyola Universities in New Orleans and the University of Louisiana in Lafayette. References Infoplease.com. (n.d.). Louisiana - Infoplease.com. Retrieved from: infoplease.com/ce6/us/A0830418.htmlState of Louisiana. (n.d.). Louisiana.gov - Explore. Retrieved from: louisiana.gov/Explore/About_Louisiana/Wikipedia. (2010, May 12). Louisiana - Wikipedia, the Free Encyclopedia. Retrieved from: http://en.wikipedia.org/wiki/Louisiana

Starbucks and Corporate Social Responsibility Case Study

Starbucks and Corporate Social Responsibility - Case Study Example This rlativ brand familiarity and th prcptin f it bing stablishd indpndntly f a glbal playr lik Starbucks may hlp initial markting ffrts. Th caus-rlatd markting initiativ cmplmnts Starbucks' rcnt fcus n incrasing its cmmitmnt t scially rspnsibl practics, including prviding thically-prducd cff. Caus-rlatd prjcts hav bcm an incrasingly ppular way f cnncting with cnsumrs as thy tap int shard attituds and valus. (Barr, 2007, 234-67) Th Starbucks Crpratin, a Sattl, WA basd cff hus, fllws sm fairly standard practics fr mting tday's thics and cmplianc. Fr businsss t rmain cmptitiv and hld rspct frm bth th businss wrld and its custmrs, a businss must striv t mt and vn xcd th lgal and thical standards that hav bcm th xpctatin tday. Starbucks mts ths bligatins by fllwing its wn cd f thics alng with mting th lgal rquirmnts and th xpctatins f its custmrs and invstrs. (Jams, 2005, 72-89) Rl f thics and CmpliancTh rl f thics and cmplianc in Starbucks financial rganizatin is up frnt and wvn int th backbn f th cmpany. All partnrs must nsur th accuracy and intgrity f Starbucks crprat rcrds.Mst imprtantly this includs rliability and accuracy f bks and rcrds, as wll as hnsty in disclsurs and in prviding infrmatin. Financial rcrds, bks f accunts, financial statmnts and rcrds f Starbucks ar maintaind in accrdanc with th rquirmnts f law and gnrally accptd accunting principls. All f Starbucks assts and liabilitis ar prprly rcrdd in its financial rcrd bks. Csts and rvnus ar rcrdd in th right tim prids. Th sal has nt fficially bn cmpltd until thr is vidnc f a sals agrmnt, th titl has passd, and th sals pric can b dtrmind and is rasnably cllctibl (Starbucks 2009). Accrding t Starbucks principals rcrding a sal until thn, wuld b a misrprsntatin f rcrds. Starbucks blivs that cnducting businss thically and striving t d th right thing is vital t th succss f th cmpany (Jams, 2005, 72- 89) Fr th third yar in a rw, thisphr Magazin has namd Starbucks as n f th Wrld's Mst thical Cmpanis. thisphr cnductd data analyss n hundrds f cmpanis basd n thir rspnss t svral survys, as wll as dcumnts and infrmatin rsarchd and rqustd by thisphr t cnfirm survy rspnss. vry cmpany was thn givn an Q scr basd n th rsults f th survy and masurd against svn distinct catgris. Ths catgris wr Crprat Citiznship and Rspnsibility; Crprat Gvrnanc; Innvatin that Cntributs t th Public Wll Bing; Industry ladrship; xcutiv Ladrship and Tn frm th Tp; Lgal, Rgulatry and Rputatin Track Rcrd; and Intrnal Systms and thics/Cmplianc Prgram (Jams, 2005, 72-89) Starbucks thical Bhavir PrcdursStarbucks has bn succssful thrughut th past dcad by cnducting businss with a strng blif in thical bhavir. As a rsult, Starbucks has arnd a rputatin as an industry ladr and rl mdl in rgards t businss thics. It is n surpris that Starbucks has bn rankd as n f "Wrld's Mst thical Cmpanis" by thisphr magazin fr thr yars in a rw(Jams, 2005, 72-89)Th fundatin f Starbucks rganizatinal cultur is utlind in th Standards f Businss Cnduct Manual. It is usd as a larning tl fr nw rcruits and can b usd as a rfrnc manual during daily pratins. Cmpany rfrncs play a

Plant and Fungus Essay Example | Topics and Well Written Essays - 500 words

Plant and Fungus - Essay Example Variably, fungi that include mushroom and yeast contribute in the preparation of beverages and are of medical value. Notably, my personal interaction with plants and fungi depicts positive results and their relevance in facilitating individual’s wellbeing. The organisms bear fruits, seeds and other products that are of high value to human life. Most people have been using the yields from the organisms as a source of food, fuel, energy and beverage. It has come into my attention that some seed plants and fungi are good medicinal products that are used in curing certain diseases that affect human development (Jabr, 2011). Secondly, the yields from the items are used in achieving nutritional balance since they provide food rich in diverse nutrients. Similarly, fungi organisms are widely depended on by most farmers as farm fertility boosters as they facilitate decomposition and recycling of organic matter (Reece, Urry, Cain, Wasserman, Minorsky, Jackson & Campbell, 2014). Farmers use them in ripening Roquefort and other products including blue cheese. From my interactions with the organisms, it is apparent that human welfare and vibrancy is dependent on the kind of food items, products one uses and the freshness of the environment. No one can thrive without consuming healthy food with superior nutritional content and breathing fresh air. It is inevitably true that I am in the business of using various types of plants and fungi, and they are affecting my life positively. In particular, I use maize, rice, wheat, mushroom and potatoes as food in most occasions. The food items constitute my favorite meals ever since, and their preference is based on the nutritional value (Reece et al, 2014). Subsequently, flowering plants such as tea, coffee and cocoa have formed key sources of my beverage. On the other hand, yeast that is a renowned type of fungi remains a vital source of my alcoholic beverage.

FINANCIAL STATEMENT ANALTSIS Essay Example | Topics and Well Written Essays - 750 words - 1

FINANCIAL STATEMENT ANALTSIS - Essay Example Section 2 provides a comparative analysis of the impact of IFRS’ adoption on financial reporting quality and capital market). Section 3 evaluates the consequences and overall impact of adoption of the IFRS in EU and Section 4 is concluding part of the essay. Accounting quality is an important aspect of financial reporting as this information serves as a strategic source for stakeholders and influences their decisions. With the adoption of the IFRS the rules and norms of financial reporting have been changed and modified, causing different opinions among various groups of stakeholders (Lopes, Cerqueira, and Brandao, 2010). It is widely debated whether the adoption of the IFRS has improved the quality of financial reporting among the EU firms (Lopes, Cerqueira, and Brandao, 2010). Thus, for example, several researchers have analysed the impact of IFRS adoption and the change in cash flows and net income, and concluded that the companies applying IAS have more value relevance of earnings, less earnings management and more timely loss recognition between the period before and after adoption of IFRS (Barth et al 2008; Christensen, Lee & Walker, 2008). These researchers believe that reliance of the IFRS leads to higher accounting quality, how ever, only in case of the firms are incentivised to be transparent and to adopt IFRS (Lopes, Cerqueira, and Brandao, 2010). According to Christensen, Lee & Walker (2008), the firms, which were forced to adopt the IFRS, did not show improvements in accounting quality. Some researchers have identified some potential problems associated with the IFRS adoption and financial reporting quality. One of the concerns related to IFRS adoption and its impact on the accounting quality is associated with risk of different interpretations of IFRS (Lopes, Cerqueira, and Brandao, 2010). Researchers determined some of the following areas for possible variations in interpretation: intangible

Luteolin and Kaempferol From Cassia Alata

Luteolin and Kaempferol From Cassia Alata LUTEOLIN AND KAEMPFEROL FROM CASSIA ALATA, ANTIMICROBIAL AND ANTIOXIDANT ACTIVITY OF ITS METHANOLIC EXTRACTS ANEELA WAHAB, TAHIRA, SABIRA BEGUM, ANJUM AYUB, IFFAT MAHMOOD, TALAT MAHMOOD, AQEEL AHMAD  AND NIDA FAYYAZ Abstract Cassia alata also known as candlebush is a medicinally important plant. In the present investigation we are reporting the isolation and structure elucidation of two flavonoids kaempferol (1) and luteolin (2) isolated from methanolic extract of its beans through bioassay guided fractionation. The structure of isolated compounds were characterized by spectroscopic techniques such as EIMS, 1H-NMR and 13C-NMR. In this article we are also presenting the antibacterial, antifungal and antioxidant activity of the methanolic extract of its leaves (CA-L), stem (CA-S) and beans (CA-BN). All the extracts showed remarkable antibacterial and weak antioxidant activity whereas moderate antifungal activity was only found in stem (CA-S) and beans (CA-BN) extracts. Introduction Cassia alata (Synonym; Senna alata) belonging to the family Leguminosae and subfamily of Fabaceae, commonly known as seven golden candlesticks, and ringworm senna (Quattrocchi U., F.L.S., 2012). This plant is native to the West Indies, tropical America, found wild almost throughout India and Pakistan (Khare C.P., 2007). C. alata with golden blooms is a summer bloomer and a striking spring that last for several weeks but prefer cooler month for flowering (Ray A.B., et al., 2010, Krishnan M. K. S., 1992). This shrub may grow up to 3 meters tall with irregular, angled, glabrous branches. Flowers have bright yellow colour. It has long, membranous, dehiscent pods with 25 or more seeds per pod (Ross I.A., 2003, Bhattacharjee S.K., 2004). Cassia alata is widely used as traditional medicine in India and Southeast Asia ( Reezal I., et al., 2002 ). This plant is reported to possess insecticidal, anti-inflammatory, hydragogue, sudorific, diuretic, pesticidal properties. Fresh leaves juice is used for ring worm, snakebite, scorpion bite, skin diseases, impetigo, syphilis sores, itching, mycosis (washerman’s itch), herpes and eczema. Roots, leaves and flowers of this plant possess many biological properties such as antibacterial, antifungal, anti-inflammatory, antitumor, expectorant and also useful in urinary tract problems (Quattrocchi U., F.L.S., 2012), asthma, bronchitis and constipation (Joshi S.G., 2000). The ethyl acetate extract of C. alata leaves possess hypoglycaemic activity (Ray A.B., et al, 2010). This plant also has hepatoprotective property. The main constituents of C.alata are flavonoids, alkaloids, anthraquinone derivatives, tannins, sterols and triterpenes (Neharkar V.S., Gaikward K.G., 2011). The pr esent paper describe the isolation and characterization of kaempferol (1) and luteolin (2). Herein we are also reporting the antimicrobial and antioxidant activities of the methanolic extract of leaves, stem and beans of this plant. All the extracts showed significant antibacterial (Table 2) and weak antioxidant activity (Table 4). Antifungal activity (Table 3) was only observed in the extract of stem and beans. Experimental Materials and Methods General: Silica gel PF254 (Merk) was used for vacuum liquid chromatography (VLC). Thin layer chromatography (TLC) was performed on pre-coated silica gel F254 (Merck). Gel permeation chromatography was performed on sephadex LH-20 (Pharmcia). The EIMS (electron impact mass spectrometery) were scanned on Jeol-JMS HX-110 mass spectrormeter. The 1H and 13C-NMR (Nuclear Magnetic Resonance) spectra were recorded on a Bruker spectrometer operating at 300 and 75 MHz respectively. The chemical shift values are reported in à ¯Ã‚ Ã‚ ¤ (ppm) relative to SiMe4 (Tetra methyl silane) as an internal standard. The coupling constant (J) is given in Hz. Plant Material: The Cassia alata was collected from Karachi (Sindh) and identified by Mr. Ghulam Rasool. A voucher specimen (86464) has been deposited in the herbarium at Department of Botany, Faculty of Science University of Karachi, Sindh Pakistan. Extraction and Isolation: The air dried leaves (7 kg), stem (5 kg) and beans (5 kg) of Cassia alata were extracted repeatedly with methanol at room temperature. The solvent was evaporated under vacuum to give 2 kg crude extract of leaves (CA-L), 3 kg crude extract of stem (CA-S) and 750 g crude extract of beans (CA-BN). The dark greenish brown gummy crude extract of beans (CA-BN) was partitioned with ethyl acetate (EtOAc), water (discard) and n-butanol fractions. Each fraction was concentrated in vacuum to have 15 g EtOAc and 15 g n-butanol soluble fractions. The EtOAc soluble fraction was further partitioned with n-hexane to obtained n-hexane soluble fraction and n-hexane insoluble fraction. The n-hexane soluble fraction (14 g) was subjected to vacuum liquid chromatography (VLC) (n-hexane: n-hexane: EtOAc in order of increasing polarity) which furnished 22 fractions (Fr-1-Fr-22). The Fr-15 was subjected to reverse-phase column chromatography using sephadex column LH-20 (CHCl3;CHCl3:MeOH in order of increasin g polarity) which yielded 12 fractions (Fr-15-1-Fr-15-12). The Fr-15-9 was further subjected to reverse phase column chromatography using sephadex column LH-20 (n-hexane:CHCl3:MeOH in order of increasing polarity) furnished 18 fractions (Fr-15-9-1-Fr-15-9-18). The Fr-15-9-10 eluted with n-hexane:CHCl3:MeOH (0.5:3:1.5) gave yellow amorphous powder which showed single spot on TLC using CHCl3: MeOH (9.2:0.8) as a solvent system was identified as kaempferol (1) (37 mg). The Fr-15-9-9 was further subjected to reverse-phase column chromatography using sephadex column LH-20 (n-hexane:CHCl3:MeOH in order of increasing polarity) which yielded 13 fractions (Fr-15-9-9-1 to Fr-15-9-9-13). The Fr-15-9-9-3 eluted with n-hexane:CHCl3:MeOH (0.5:3:1.5) showed single spot on TLC (CHCl3:MeOH, 9.2:0.8) appeared as yellowish powder and was identified as luteolin (2) (27 mg). Biological assay: Screening of antibacterial activity: The disc diffusion method (Bauer et al, 1966) was used to determine the antibacterial activity of methanolic extracts. 100 mg/ml of stock solution was prepared by dissolving extracts in DMSO. Sterile filter discs containing 10 à ¯Ã‚ Ã‚ ­l of stock solution were used for screening. The Mueller Hinton agar (Oxoid) plates were seeded with 24 hours old culture grown in Mueller Hinton broth (Oxoid). The prepared discs were placed onto the surfaces at different positions and plates were incubated at 37à ¯Ã¢â‚¬Å¡Ã‚ °C for 24 hours. Results were recorded by measuring the zone of inhibitions in mm. Gentamicin was used as a standard. Screening of antifungal activity: Antifungal activity was also determined by disc diffusion method (Bauer et al, 1966) as above. Briefly, a small amount of culture was transferred to 2-3 ml distilled water or normal saline in a screw capped tube with few glass beads (1 mm in diameter) and vortexes for 5-10 minutes to make a homogeneous suspension of fungal culture. Sabouraud dextrose agar (SDA) plates were seeded with this suspension. Sterile filter discs containing 10 à ¯Ã‚ Ã‚ ­l of stock solution were placed onto the surfaces at different positions. Plates were incubated at room temperature for 1 week. Results were recorded by measuring the zone of inhibitions in mm. Gresiofulvin was used as a standard. Determination of minimum inhibitory concentration (MIC): MIC of methanolic extracts were determined by the disc diffusion method ( Bauer et al, 1966). Sterile discs containing different concentrations of samples varying from 0.98 to 1000 à ¯Ã‚ Ã‚ ­g per disc were prepared. The MIC of those extracts showing maximum zone of inhibition against microorganism were calculated ( Table 2 ). Antioxidant activity: Antioxidant activity was determined by using the method described by Lee et al. (1998). 1,1-diphenyl-2-picrylhydrazyl (DPPH) was prepared in ethanol (300  µM). 10  µL of each extract and 90 ÃŽ ¼L solution of stable radical, 1,1-diphenyl-2-picrylhydrazyl (DPPH) was added in 96 well micro titer plates and incubated at 37 º C for 30 minutes. Absorbance was measured at 515 nm by using a spectrophotometer. Percent inhibition of radicals by treatment of test sample was determined by comparison with a DMSO treated control group. % Inhibition = (absorbance of the control-absorbance of the test sample) x 100 Absorbance of the control Ascorbic acid was used as standard control. The EC50 value calculated denotes the concentration (in ug/ml) of sample required to scavenge 50% of DPPH Characterization of Kaempferol (1) Yellow amorphous powder. 1H-NMR à ¯Ã‚ Ã‚ ¤ (300 MHz, CD3OD): 8.09 (2H, d, J = 8.7 Hz, H-2’, 6’), 6.91 (2H, d, J = 8.7 Hz, H-3’, 5’), 6.43 (1H, d, J = 1.8 Hz, H-8), 6.19 (1H, d, J = 1.8 Hz, H-6). EIMS m/z: 286 [M]+. 13C-NMR (see Table 1). All data were identical with that of reported in literature (Hadizadeh F., et al, 2003, Gangwal A., et al, 2010). Characterization of Luteolin (2) Yellow amorphous powder. 1H- NMR à ¯Ã‚ Ã‚ ¤ (300 MHz, CD3OD): 7.39 (1H, dd, J = 9.0, 1.8 Hz, H-6’) ,7.36 (1H, d, J = 1.8 Hz, H-2’), 6.88 (1H, d, J = 9.0, Hz, H-5’), 6.53 (1H, s, H-3), 6.43 (1H, d, J = 1.8 Hz, H-8), 6.19 (1H, d, J = 1.8 Hz, H-6). EIMS m/z: 286 [M]+. 13C-NMR (see Table 1). All data were identical with that of reported in literature (Saeidnia S., et al, 2009). Results and discussion: The phytochemical investigation of the methanolic extracts of Cassia alata beans resulted in the isolation of kaempferol (1) and luteolin (2). Compound (1) showed molecular ion peak at m/z 286 having molecular formula C15H10O6. Its 1H-NMR spectrum showed the characterstic peak of H-2’ and 6’ as a doublet at à ¯Ã‚ Ã‚ ¤Ãƒ ¯Ã¢â€š ¬Ã‚  Ãƒ ¯Ã¢â€š ¬Ã‚ ¸Ãƒ ¯Ã¢â€š ¬Ã‚ ®Ãƒ ¯Ã¢â€š ¬Ã‚ °Ãƒ ¯Ã¢â€š ¬Ã‚ ¹Ãƒ ¯Ã¢â€š ¬Ã‚  with ortho coupling of 8.7 Hz whereas H-3’ and 5’ with similar ortho coupling appeared at à ¯Ã‚ Ã‚ ¤Ãƒ ¯Ã¢â€š ¬Ã‚  6.91 as a doublet.1H-NMR spectrum of 1 further displayed signals of aromatic protons as a doublet at à ¯Ã‚ Ã‚ ¤Ãƒ ¯Ã¢â€š ¬Ã‚  Ãƒ ¯Ã¢â€š ¬Ã‚  6.19 (H-6) and at à ¯Ã‚ Ã‚ ¤Ãƒ ¯Ã¢â€š ¬Ã‚   6.43 (H-8) showing meta coupling of 1.8 Hz. The EIMS spectrum of compound (2) is similar to (1) having same molecular mass (m/z 286) and formula (C15H10O6). In the 1H-NMR spectrum of 2 characterstic peak of H-3 appeared at à ¯Ã‚ Ã‚ ¤Ãƒ ¯Ã¢â€š ¬Ã‚  6.53 as a singlet. Other important signals observed at à ¯Ã‚ Ã‚ ¤Ãƒ ¯Ã¢â€š ¬Ã‚  6.88 (d, J = 9.0, Hz, H-5’), à ¯Ã‚ Ã‚ ¤Ãƒ ¯Ã¢â€š ¬Ã‚  7.36 (d, J = 1.8 Hz, H-2’) and à ¯Ã‚ Ã‚ ¤Ãƒ ¯Ã¢â€š ¬Ã‚  7.39 (dd, J = 9.0, 1.8 Hz, H-6’). The aromatic protons H-6 and H-8 showed same à ¯Ã‚ Ã‚ ¤Ãƒ ¯Ã¢â€š ¬Ã‚  and J value as in compound 1. The 13C-NMR spectrum (Table 1) of both compounds 1 and 2 displayed signals of nine quaternary and six methine carbons . All the 13C assignments are in agreement with the reported data (Gangwal A., et al, 2010, Saeidnia S., et al, 2009). The results of antibacterial activity indicated that all the methanolic extracts of C. alata (CA-L, CA-S and CA-BN) have potential to kill various pathogenic gram+ve and gram-ve bacteria (Table 2), whereas good antifungal activity was observed in CA-S and CA-BN extracts against Fusarium specie (Table 3). All the extracts (CA-L, CA-S and CA-BN) showed less than 50% inhibition of DPPH radicals in antioxidant activity (Table 4). CONCLUSION: The known flavonoids kaemferol (1) and luteolin (2) were isolated from the methanolic extracts of C. alata beans. The structure of the isolated compounds were elucidated by various spectroscopic techniques. Pharmacological investigations have indicated that all the extracts (CA-L, CA-S and CA-BN) of this plant possess significant antimicrobial and weak antioxidant activity. References: Bauer, A.W., Kirby, W.M.M., Sherris, J.C., Turck, M. (1966). Antibiotic susceptibility testing by a standardized single disk method. American Journal of Clinical Pathology, 45, 493–496. Bhattarchrjee, S.K. and Michael,A.M. (2004). Hand Book of Medicinal Plants. Pointer Publishers Jaipur 302003 (Raj), India, pp. 77-78. Gangwal, A., Parmar, S.K., Sheth, N.R. (2010). Vol. 2(1). Triterpenoid, flavonoids and sterols from Lagenaria siceraria fruits. Scholars Research Library. pp. 307- 317. Hadizadeh, F., Noaman, K., Hossein, H., Randa, K.A. (2003). Kaempferol from Saffron Petals. Iranian Journal of Pharmaceutical Research. pp. 251-252. Joshi, S.G. (2000). Medicinal Plants. Oxford and IBH publishing Co.Pvt. Ltd, New Delhi, Calcutta, India, pp. 117. Khare, C.P. (2007). Indian Medicinal Plants.Springer.New Delhi, India, pp.126. Krishnan, M.K.S. (1992). Vol.3. The Wealth of India. Council of Scientific and Industrial Research New Delhi, India, pp. 328. Lee, S. K., Zakaria, H., Chuyng, H. L., Kuyengl, L.,Games, E. J. C., Mehta, R. J., Kinghorn, D., and Pezzuto, J. M. (1998). Evaluation of the antioxidant potential of natural products.Combinatorial Chemistry and High Throughput Screening.1: 35-4 Neharkar, V.S., Gaikwad, K.G. (2011). Vol. 2(1). Hepatoprotective activity of Cassia alata (Linn.) leaves against Paracetamol-induced hepatic injury in rats. Research Journal of Pharmaceutical, Biological and Chemical Sciences: pp. 783-788. Quattrocchi, U., F.L.S. (2012). Vol.5 R-Z: CRC World Dictionary of Medicinal and Poisonous Plants. CRC Press Taylor Francis Group Boca Raton New York, USA, pp. 236-237. Ray, A.B., Chansouria, J.P.N. and Hemalatha, S. (2010). Medicinal Plants: antidiabetic and Hypoglycaemic Activities. ibdc Publishers Lucknow, India, pp. 95. Ross, I.A. (2003). vol.1. Medicinal Plants of the World. Humana Press, Totowa, New Jersey, pp. 165-166. Reezal, I., Somchit, M. N. and Abdul Rahim, M. (2002). Vol.1. In vitro Antifungal Properties of Cassia alata (GELNGGANG BESAR). Proceedings of the Regional Symposium on Environment and Natural Resources. pp. 654-659. Saeidnia, S., Yassa, N., Rezaeipoor ,R., Shafiee, A., Gohari, A. R., Kamalinejad, M., Gooderzy, S. (2009). Vol. 17(1). Immunosuppressive principles from Achillea talagonica, an endemic species of Iran. Journals.tums.ac.ir: pp. 37-41. Table 1. C13-NMR spectral data of kaempferol (1) and luteolin (2) in CD3OD (ppm) at 75 MHz Table 2. Antibacterial activity of different extracts of Cassia alata (zone of inhibition in mm) CA-L= Cassia alata Leaves, CA-S = Cassia alata Stem, CA-BN = Cassia alata Beans. Table 3. In Vitro Antifungal activity (zone of inhibition in mm) Table 4. Antioxidant activity of Methanolic extracts of C.alata

Paleys Arguement From Design, And Humes Counter-analogy :: essays research papers

Hume’s counter-analogy does not succeed in undermining Paley’s argument from design. Paley clearly explains to his reader that humans are so complicated that we must have been made by a designer. Hume argues that since the universe is not a human art, and is more like an animal, it does not need a designer. Paley argues that the complexity and functionality of a watch clearly shows that it was made by a designer. Animals are also complex and functional, therefore, Hume does not change the argument adequately enough to effectively counter it.   Ã‚  Ã‚  Ã‚  Ã‚  Paley lays his argument as such: a watch is like the universe in complexity and functionality, a watch needs a designer, therefore, the universe needs a designer as well. Paley’s argument centers around the simile between a watch and the universe . He points out that the watch is complicated with many parts, yet all work together to form a functional machine. Paley shows in his argument that all the pieces of the watch are put together for a definite purpose. No matter how many watches were made before this one, Paley explains that the watch still has a maker. Watches cannot be designed by other watches, some superior being must have created at least the first one. The designer obviously understands how the watch works and how to create it to function properly.   Ã‚  Ã‚  Ã‚  Ã‚  With this premise, Paley introduces the connection between the watch and our universe. He explains clearly that if a watch needs a designer, surely the far more complex universe should need one to. Paley justifies the existence of God through this watch and universe simile. He concludes that if a watch needs a superior designer, then the universe needs a maker as well, this maker being God.   Ã‚  Ã‚  Ã‚  Ã‚  Hume attempts to counter Paley’s argument by saying that the universe is more like an animal than a work of human art. He says that because the universe is not a human art, it does not need a maker, just as animals do not need makers. Therefore, Paley argues, the universe also does not need a designer, and because of this, God does not exist. Hume does not effectively counter Paley’s argument because he simply replaces a complex watch with an even more complex animal in his statements. He does not successfully address the fact that animals were at some point created as well. Paleys Arguement From Design, And Humes Counter-analogy :: essays research papers Hume’s counter-analogy does not succeed in undermining Paley’s argument from design. Paley clearly explains to his reader that humans are so complicated that we must have been made by a designer. Hume argues that since the universe is not a human art, and is more like an animal, it does not need a designer. Paley argues that the complexity and functionality of a watch clearly shows that it was made by a designer. Animals are also complex and functional, therefore, Hume does not change the argument adequately enough to effectively counter it.   Ã‚  Ã‚  Ã‚  Ã‚  Paley lays his argument as such: a watch is like the universe in complexity and functionality, a watch needs a designer, therefore, the universe needs a designer as well. Paley’s argument centers around the simile between a watch and the universe . He points out that the watch is complicated with many parts, yet all work together to form a functional machine. Paley shows in his argument that all the pieces of the watch are put together for a definite purpose. No matter how many watches were made before this one, Paley explains that the watch still has a maker. Watches cannot be designed by other watches, some superior being must have created at least the first one. The designer obviously understands how the watch works and how to create it to function properly.   Ã‚  Ã‚  Ã‚  Ã‚  With this premise, Paley introduces the connection between the watch and our universe. He explains clearly that if a watch needs a designer, surely the far more complex universe should need one to. Paley justifies the existence of God through this watch and universe simile. He concludes that if a watch needs a superior designer, then the universe needs a maker as well, this maker being God.   Ã‚  Ã‚  Ã‚  Ã‚  Hume attempts to counter Paley’s argument by saying that the universe is more like an animal than a work of human art. He says that because the universe is not a human art, it does not need a maker, just as animals do not need makers. Therefore, Paley argues, the universe also does not need a designer, and because of this, God does not exist. Hume does not effectively counter Paley’s argument because he simply replaces a complex watch with an even more complex animal in his statements. He does not successfully address the fact that animals were at some point created as well.

Social Network and Dangerous New Form

Instagram can be a dangerous new form of social networking. Smart phone users now have an option to download an app called Instagram. Although it is the new, trendy thing to do, it can be an issue. The basics of Instagram are to post only pictures. Users can put a small bio about themselves, but it is nothing like the other social networks where users will post all sorts of pointless information. When a picture is posted, users can put a caption for it and the caption is often followed by things called ‘hashtags’.Examples of these include #pretty, #somuchfun #beach, or whatever it is pertaining to the photo. In the search section, users can search for words or phrases that have been hashtagged. There are choices to â€Å"follow† other Instagram users, but the main issue is that of the user doesn’t want to be followed by somebody, they have no choice. On other social networks, there is an option to accept or decline followers, but on Instagram there is not. Instagram is generally used by people between the ages of 14 and 25, which makes it a lot worse that there is no way to keep away potentially dangerous users.When somebody searches for a hashtag, every use of that hashtag by every Instagram user pops up. There is no need to be following a person to look and â€Å"like† their pictures. Although there is an option to set your Instagram profile as private, only a minority of people actually do it. I have and use my Instagram every day. I love it. I think it is great to be able to only post pictures and to only be able to see pictures that others have posted.My main stream of pictures doesn’t get all crowded up with people posting pointless statuses about their life and annoying political references. I do have negative thoughts about it though. I hate it when strangers like or comment on pictures that I post. I am being followed by people I have never met and no nothing about and I cannot do anything about it. I am sure to only post pictures that don’t show where my location is or put any captions about there I live. I would hate to see some horrendous things happen to users of Instagram because of ignorant mistakes like that.

Free Essays on Private Threating Enviroments

Private Threatening Environments 1 Running head : THE IMPLICATIONS OF THREATENING EVIRONMENTS ON INTELLECTUAL PROCESSING Do High-Achieving Female Students Underperforming in Private? The Implications of Threating Environments on Intellectual Processing Alcorn State University Private Threatening Environments 2 Ben-Zeev, T & Inzlicht, M. (2003). Do High-Achieving Female Students Underperforming in Private The Implications of Threatening Eviornments on Intellectual Processing. Journal of Educational Psychology Summary of Article Education statiatics show that a very small amount of women are in the field of math and science. Although women represent over half of the student body, they are a small percentage that graduate in math and science. (National Science Foundation,200). The authors look at the question, how under representation of females reflect gender makeup, tokenism, and stereotypes in classrooms. It can also explain how females perform under the pressure of negative stereotypes in math and science. The authors make an argument that the females in a group adds the awareness of ones gender which increases negative stereotypes associated with that. The authors indentify that the females who cared the most about doing seemed to be affected the most by the pressures of stereotypes. In this study the authors examine how the students performed or unperformed in a private or public setting. The authors concentrated on females who were identified as being good in math. They attempted to evaluate the female students and how they affected by situations and stereotypes. The authors did a good job of getting data by controlled evaluation and other accurate research information already available. The research leans to the assumption that work in public adds pressure to the threat of stereoty... Free Essays on Private Threating Enviroments Free Essays on Private Threating Enviroments Private Threatening Environments 1 Running head : THE IMPLICATIONS OF THREATENING EVIRONMENTS ON INTELLECTUAL PROCESSING Do High-Achieving Female Students Underperforming in Private? The Implications of Threating Environments on Intellectual Processing Alcorn State University Private Threatening Environments 2 Ben-Zeev, T & Inzlicht, M. (2003). Do High-Achieving Female Students Underperforming in Private The Implications of Threatening Eviornments on Intellectual Processing. Journal of Educational Psychology Summary of Article Education statiatics show that a very small amount of women are in the field of math and science. Although women represent over half of the student body, they are a small percentage that graduate in math and science. (National Science Foundation,200). The authors look at the question, how under representation of females reflect gender makeup, tokenism, and stereotypes in classrooms. It can also explain how females perform under the pressure of negative stereotypes in math and science. The authors make an argument that the females in a group adds the awareness of ones gender which increases negative stereotypes associated with that. The authors indentify that the females who cared the most about doing seemed to be affected the most by the pressures of stereotypes. In this study the authors examine how the students performed or unperformed in a private or public setting. The authors concentrated on females who were identified as being good in math. They attempted to evaluate the female students and how they affected by situations and stereotypes. The authors did a good job of getting data by controlled evaluation and other accurate research information already available. The research leans to the assumption that work in public adds pressure to the threat of stereoty...

Dolci and Stomer essays

Dolci and Stomer essays Over the centuries, picturing religious events in the form of artwork was still very popular and important. However, the way or style in which the events were pictured changed. The cultural production of the seventeenth and early eighteenth centuries is often described as the baroque period. Among the most noted Italian Baroque painters were Caravaggio and Carracci, whose different styles were both in line with the period. Through copies of their paintings and styles being taught in art schools, their influence on later artists inside and outside of Italy has been enormous. Carlo Dolci and Mathias Stomer are each painters that were influenced by the style of Caravaggio and Carracci. Stomers painting, The Judgment of Solomon (1640), shows an influence of Caravaggio, where Dolcis painting, Virgin and Child with Saint John the Baptist (1636) shows an influence of the style of Carracci. Stomers style of painting is closely related to that of Caravaggio (1573-1610). Caravaggio, an Italian baroque painter, naturalized both religion and the classics in his art where he reduced them to human dramas played out in the cruel and grimy settings of his time and place. He often used perspective and chiaroscuro to bring viewers as close to the action of the painting as possible to give viewers a feel as if they were actually participating. Caravaggio also used dark setting that enveloped their occupants called tenebrism or shadow manner. Upon first glance of the painting, The Judgment of Solomon, the viewers eyes are taken to a single point of illumination near a picture of a beautiful new born hanging upside down by a man ready to slaughter it. There is great attention given to shading and the illumination of light. Stomer shows great talent in painting muscular figures by the look of the man holding the sword and of the two infants. The clothes on each person are pictured as free ...

1.Compare and contrast US naval innovation with that of Great Britain Essay

1.Compare and contrast US naval innovation with that of Great Britain. What is the dichotomy and why Use evidence from (REQUIRED READINGs) to substantiate your argument - Essay Example The United States did not heed the treaties that Great Britain recommended. They saw the need to build submarines and the advantage of using them in battle. Their naval officers highlighted the benefits of submarines during naval warfare. In conclusion, Great Britain adopted a defense-based approach whereas United States was concerned with offensive-based equipment to counter the threats posed by nations like Japan. This was evidenced by the different retaliation strategies to the German submarine threat, the Versailles treaty and different strategies for budgeting for war. US came into World War I immediately after Germany resorted into using submarines in naval warfare. By using submarines, the Germans nearly forced Great Britain out of the first war. For this reason, countries had to invest into the innovation of new weapons to counter the threat of their adversaries. The United States, after the attack on Pearl Harbor by the Japanese, began to see the need of engaging in naval warfare. The attack forced the issuance of orders, by the US Navy, to discriminate against Japanese air and naval warfare. Following the raids on their vessels, the British Navy marshaled the US Navy to abolish the use of submarines in naval warfare. However, the United States did not approve the abolition of the submarine1. The US created a submarine section in its naval force as they planned to protect themselves from an ambitious Japan. Capt. Thomas C. Hart argued that â€Å"the submarine will be an extremely valuable weapon†¦..† The submarines at the disposal of the US Navy, during the First World War, were not seaworthy and not as useful. Great Britain, unlike it counterpart the US, saw the need for a capital ship and valued the decisive nature of a fleet. This approach, according to Correlli Barnett, was misguided and resulted into the disastrous Washington treaty2. The Washington treaty showed the ‘penny-pinching’ side of the British

Itlalian Literature Essay Example | Topics and Well Written Essays - 500 words

Itlalian Literature - Essay Example ThÐ µ LÐ µopÐ °rd wÐ °s pÐ °rt of Ð ° post-wÐ °r trÐ µnd Ð °mong ItÐ °liÐ °n intÐ µllÐ µctuÐ °ls to scrutinizÐ µ, if not chÐ °llÐ µngÐ µ, thÐ µ vÐ µry principlÐ µ of ItÐ °liÐ °n politicÐ °l unificÐ °tion, sÐ µtting thÐ µ stÐ °gÐ µ for ItÐ °lys nÐ µw fÐ µdÐ µrÐ °lism, Ð ° vÐ µry concrÐ µtÐ µ rÐ µÃ °lity todÐ °y. It wÐ °s this pÐ µrspÐ µctivÐ µ, morÐ µ thÐ °n thÐ µ story itsÐ µlf, which dÐ µfinÐ µd ThÐ µ LÐ µopÐ °rd Ð °s Ð ° clÐ °ssic work of ItÐ °liÐ °n (Ð °nd intÐ µrnÐ °tionÐ °l) litÐ µrÐ °turÐ µ, for othÐ µr books hÐ °d bÐ µÃ µn writtÐ µn Ð °bout thÐ µ SiciliÐ °n grÐ °ciousnÐ µss. Still, to portrÐ °y thÐ µ story of thÐ µ dÐ µclining SÐ °linÐ °s in thÐ µ 1860s Ð °s Ð ° mÐ µrÐ µ fÐ °blÐ µ for thÐ µ dÐ µclinÐ µ of thÐ µ ItÐ °liÐ °n monÐ °rchy Ð °nd socio-politicÐ °l Ð µstÐ °blishmÐ µnt in thÐ µ 1940s is to ovÐ µrlook thÐ µ novÐ µllÐ °s prÐ µvÐ °lÐ µnt Ð °ppÐ µÃ °l. It dÐ µÃ °ls with thÐ µ Church, swÐ µÃ µping sociÐ °l chÐ °ngÐ µ Ð °nd, of coursÐ µ, lovÐ µ. ThÐ µ LÐ µopÐ °rd is thÐ µ story Ð °bout Don FÐ °brizio, PrincÐ µ of SÐ °linÐ °, Ð ° guy who turnÐ µd forty Ð °nd hÐ °vÐ µ sÐ µvÐ µrÐ °l childrÐ µn. HÐ µ is Ð ° sort of compÐ °ssionÐ °tÐ µ tyrÐ °nt in his housÐ µhold, Ð ° mÐ °n of Ð ° vÐ µry old fÐ °mily, Ð °ccustomÐ µd to knowing his plÐ °cÐ µ Ð °nd to hÐ °ving people over that he actually knows. ThÐ µ PrincÐ µ is Ð °lso Ð ° mÐ °n of grÐ µÃ °t corporÐ µÃ °l Ð °ppÐ µtitÐ µs, lÐ °ckÐ °dÐ °isicÐ °l with his monÐ µy (though not wÐ °stÐ µful or lÐ °vish), politicÐ °lly wÐ µll-informÐ µd but complÐ µtÐ µly Ð °politicÐ °l in Ð °ction, Ð °nd Ð °lso Ð °n Ð °mÐ °tÐ µur Ð °stronomÐ µr of somÐ µ notÐ µ. WhÐ µn thÐ µ story opÐ µns, thÐ µ RisorgimÐ µnto is ongoing, but it is clÐ µÃ °r thÐ °t it will bÐ µ ultimÐ °tÐ µly succÐ µssful, Ð °nd thÐ °t thÐ µ Kingdom of thà  µ Two SiciliÐ µs will bÐ µ Ð °bsorbÐ µd into thÐ µ nÐ µwly unitÐ µd, somÐ µwhÐ °t morÐ µ dÐ µmocrÐ °tic, ItÐ °ly. Don FÐ °brizio nominÐ °lly supports thÐ µ old rÐ µgimÐ µ, but hÐ µ rÐ µÃ °listicÐ °lly stÐ °ys out of thÐ µ conflict. His fÐ °voritÐ µ nÐ µphÐ µw, TÐ °ncrÐ µdi, thÐ µ impovÐ µrishÐ µd but chÐ °rismÐ °tic son of his sistÐ µr, is Ð °n fÐ µrvÐ µnt supportÐ µr of GÐ °ribÐ °ldi, who Ð °t thÐ °t timÐ µ wÐ °s Ð ° lÐ µÃ °dÐ µr of thÐ µ rÐ µvolution. SÐ µvÐ µrÐ °l long